The Zeiss Cell Discoverer 7 with the LSM 900 Confocal Microscope is a fully integrated, high-end imaging system that offers a variety of incubation and detection options.

It provides higher throughput, achieving up to 9 times faster wide-field imaging and 1.8 times faster confocal image acquisition.

This system features a broad spectral range with seven excitation LED lines, including a 735 nm far-red option, ensuring optimal performance with wide-field mode. The LSM 900 system uses four lasers with wavelengths ranging from 405 nm to 640 nm.

The Zeiss Cell Discoverer 7 supports a wide range of dyes and incorporates advanced workflows to enhance guided acquisition. It fully supports auto-immersion objectives and offers automated sample focusing, enabling rapid identification of the region of interest. Additionally, the Definite Focus system maintains the focal position throughout live-cell experiments, even over extended periods.

The system also automatically generates focus maps for multiple positions in long-term time-lapse experiments and enables cyclic imaging with different sample carriers for advanced time-series analysis. The new sample holder maximizes the travel range for full chamber-slide coverage, ensuring system uptime through extensive endurance testing.

Sample Carriers

1x Petri Dish 35 mm, 1x Petri Dish 60 mm, 2x chamber 2x short, 2x chamber 4x short, 2x chamber 8x short, 2x Slide-Long, 2x Slide-Short, 3x Slide, 6x Petri dish, Multichamber 1536, Multichamber 384, Multichamber 96, Multiwell 12, Multiwell 24, Multiwell 384, Multiwell 48, Multiwell 6, Multiwell 96 small, Multiwell 96.

Applications

1. Live Cell Imaging with LED Technology:

The Cell Discoverer 7 offers exceptionally gentle imaging at faster speed, with low photo toxicity, and enables high-resolution fluorescence imaging of both transfected and non-modified live cell cultures.

2. Forster Resonance Energy Transfer (FRET):

Forster Resonance Energy Transfer is a powerful and sensitive technique used to study protein-protein interactions and monitor molecular dynamics. It is widely applied in biophysical research, allowing scientists to measure interactions and distances at the nanometer scale, providing valuable insights into the dynamics of biomolecules such as proteins and nucleic acids.

3. Fluorescence Recovery after Photo bleaching (FRAP):

It is a powerful and widely used technique in biological and biochemical research that enables real-time analysis of molecular dynamics within living cells, facilitating the study of membrane dynamics, protein interactions, and cell organization while providing quantitative measurements of diffusion coefficients and binding constants across a diverse range of molecules.

4. Imaging Large Model Organisms and Various Models:

From insects to amphibians, plants to fish, mice, and more, explore your options for high-resolution imaging of large specimens. Multi-labeled living tissue sections, organs, small organisms, organotypic spheroids, or cell culture preparations are all included.

5. Target and Lead Identification in Drug Discovery:

Explore microscopy solutions to identify the most promising targets and leads for actionable insights from drug screening.

6. High-content screening:

Quickly acquire high-resolution images of multi-labeled cell cultures from various sample carriers, such as multi-well plates, multiwell chambers, Petri dishes, fixed slides, etc.